Weather looks OK right now, I bet that it will be optimal time to run the Dragon. Iron horse motorcycle resort is a good place to lay your head, if they are open.
I second the parkway, you can drop down to Winston on 421 I bet. On a side note, 421 in Tenn is fantastic, past Mountain City. The Snake its called. Shady Valley TN.
Right now between of Asheville and NC80 the parkway is closed due to weather. I personally find the parkway to be the best riding in the area, and that does include the Dragon. If you feel a need to go up on the north side I would recommend NC80, aka The Devils Whip to get you up there. 226A is ruined, 181 is not bad. If you want to hit the parkway, let me know, I will get you much better directions. South side I am not so familiar with, but SC1 and I want to say 176 up to the parkway are national favorites.
Be prepared for sensory overload. And wildlife, the turkeys in particular are running in gangs.
So in my rambling way I will say: SC1 to 176 to Parkway to -oh this is nice - 74A in Asheville, 9 to Old Fort Mountain Road, Silvers Welch to 70 to 80 to Parkway to 421 to Shady Valley to Winston Salem. Past that I dont know. I can make you a map if you want.